Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558467 | 0.79 | NPSR1 (0.38) | CHRM1ALDH1A1 | |
| SCHEMBL8519318 | 0.77 | CHRM1 (0.48) | CHRM1ALDH1A1SLC6A4 | |
| SCHEMBL13992792 | 0.73 | ALDH1A1 (0.38) | CHRM1ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL23595697 | 0.73 | — | — | |
| SCHEMBL23595698 | 0.73 | — | — | |
| SCHEMBL8413432 | 0.72 | PRCP (0.45) | CHRM1SLC6A4SLC6A3 | |
| SCHEMBL8410312 | 0.72 | PRCP (0.45) | CHRM1SLC6A4SLC6A3 | |
| SCHEMBL8410313 | 0.72 | PRCP (0.45) | CHRM1SLC6A4SLC6A3 | |
| SCHEMBL13992800 | 0.71 | SLC6A4 (0.38) | CHRM1ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL23595680 | 0.69 | HDAC4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972952-A | THERAPY FOR STROKE, NERVOUS SYSTEM DISORDERS, ALZHEIMER'SDISEASE | LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-10-26 | — | — | US | disclosed |