Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413432 | 1.00 | PRCP (0.45) | PRCPCHRM1SIGMAR1SMARCA2SMARCA4 | |
| SCHEMBL8410312 | 1.00 | PRCP (0.45) | PRCPCHRM1SIGMAR1SMARCA2SMARCA4 | |
| SCHEMBL8520711 | 0.77 | PRCP (0.40) | PRCPCHRM1SIGMAR1 | |
| SCHEMBL8560436 | 0.77 | PRCP (0.40) | PRCPCHRM1SIGMAR1 | |
| SCHEMBL23595970 | 0.77 | SIGMAR1 (0.56) | PRCPSIGMAR1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL5171390 | 0.77 | SIGMAR1 (0.56) | PRCPSIGMAR1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL24462837 | 0.77 | SIGMAR1 (0.56) | PRCPSIGMAR1GRIN2DGRIN3BCYP2B6 | |
| Gacyclidine SCHEMBL4465879 | 0.73 | SIGMAR1 (0.57) | PRCPCHRM1SIGMAR1CHRM2CHRM4 | |
| Gacyclidine SCHEMBL7190367 | 0.73 | SIGMAR1 (0.57) | PRCPCHRM1SIGMAR1CHRM2CHRM4 | |
| Gacyclidine SCHEMBL3457748 | 0.73 | SIGMAR1 (0.57) | PRCPCHRM1SIGMAR1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972952-A | THERAPY FOR STROKE, NERVOUS SYSTEM DISORDERS, ALZHEIMER'SDISEASE | LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-10-26 | — | — | US | claimed |
| US-5972952-A | THERAPY FOR STROKE, NERVOUS SYSTEM DISORDERS, ALZHEIMER'SDISEASE | LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-10-26 | — | — | US | disclosed |