SCHEMBL8520735

SCHEMBL8520735

C=CC=CCN1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.38
HRH3 Q9Y5N1 5/20 0.34
LTA4H P09960 1/20 0.34
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
MAPT P10636 1/20 0.33
HRH4 Q9H3N8 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30
PRMT8 Q9NR22 1/20 0.30
CHRM5 P08912 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22972376 1.00 SIGMAR1 (0.38) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
Hydrochloric Acid SCHEMBL2704381 0.98 SIGMAR1 (0.37) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
SCHEMBL16215907 0.98 SIGMAR1 (0.36) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
SCHEMBL19720569 0.98 SIGMAR1 (0.36) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
SCHEMBL9112196 0.79 SIGMAR1 (0.41) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
SCHEMBL9112203 0.79 SIGMAR1 (0.41) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
SCHEMBL23872301 0.79 HRH3 (0.43) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
SCHEMBL7227482 0.79 HRH3 (0.43) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
SCHEMBL10748748 0.79 HRH3 (0.43) SIGMAR1HRH3LTA4HCHRNB2CHRNB4
SCHEMBL818010 0.77 HRH3 (0.41) SIGMAR1HRH3MAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11070301-A None JP disclosed
CN-107522651-A A kind of method by palladium chtalyst synthesis of indole quinoline derivant 台州学院 2017-12-29 CN disclosed
JP-H1170301-A TREATMENT AGENT FOR WATER CONTAINING WASTE COATING MATERIAL IPPOSHA OIL IND CO LTD 1999-03-16 JP disclosed