Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520931 | 0.86 | FFAR1 (0.49) | KMT2AMEN1NPC1NR1H4FFAR1 | |
| SCHEMBL8520753 | 0.85 | KMT2A (0.48) | KMT2AMEN1NPC1ITGB3ITGA2B | |
| SCHEMBL7498241 | 0.84 | KMT2A (0.39) | KMT2AMEN1NPC1ITGB3ITGA2B | |
| SCHEMBL7506968 | 0.81 | KMT2A (0.46) | KMT2AMEN1NPC1ITGB3ITGA2B | |
| SCHEMBL7457481 | 0.80 | NR1H4 (0.67) | KMT2AMEN1ITGB3ITGA2BNR1H4 | |
| SCHEMBL7506889 | 0.79 | ITGB3 (0.64) | ITGB3ITGA2BNR1H4ITGB1ITGAV | |
| SCHEMBL7510036 | 0.78 | CA12 (0.49) | KMT2AMEN1NPC1ITGB3ITGA2B | |
| SCHEMBL7373424 | 0.77 | ITGB3 (0.64) | KMT2AMEN1ITGB3ITGA2BNR1H4 | |
| SCHEMBL7452327 | 0.77 | ITGB3 (0.53) | KMT2AMEN1NPC1ITGB3ITGA2B | |
| SCHEMBL7377112 | 0.77 | ITGB3 (0.55) | KMT2AMEN1NPC1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997036860-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |