Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406916 | 0.94 | NPC1 (0.50) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8408944 | 0.87 | NPC1 (0.47) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL258759 | 0.84 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL29494818 | 0.84 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL31267541 | 0.84 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8408061 | 0.81 | PARP1 (0.39) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8409283 | 0.80 | PARP1 (0.39) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8408907 | 0.80 | PARP1 (0.39) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8406938 | 0.80 | NPC1 (0.37) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL10061927 | 0.80 | NPC1 (0.64) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11291634-A | — | — | None | — | — | JP | disclosed |
| JP-H11291634-A | HEAT-SENSITIVE RECORDING BODY | OJI PAPER CO LTD | 1999-10-26 | — | — | JP | disclosed |