Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406938 | 0.91 | NPC1 (0.37) | PARP1NPC1RAB9APOLBLMNA | |
| SCHEMBL8406916 | 0.86 | NPC1 (0.50) | PARP1NPC1RAB9APOLBLMNA | |
| SCHEMBL8409154 | 0.85 | NPC1 (0.35) | PARP1NPC1RAB9APOLBLMNA | |
| SCHEMBL8408061 | 0.84 | PARP1 (0.39) | PARP1NPC1RAB9APOLBLMNA | |
| SCHEMBL20363907 | 0.84 | NPC1 (0.47) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8408907 | 0.83 | PARP1 (0.39) | PARP1NPC1RAB9APOLBLMNA | |
| SCHEMBL26658010 | 0.80 | NPC1 (0.46) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8520769 | 0.80 | NPC1 (0.51) | PARP1NPC1RAB9APOLBLMNA | |
| SCHEMBL14324336 | 0.79 | IDH1 (0.44) | NPC1RAB9APOLBLMNAIDH1 | |
| SCHEMBL8409285 | 0.77 | MAP3K7 (0.39) | POLBLMNAALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |