Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408943 | 0.88 | NPC1 (0.36) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8520769 | 0.87 | NPC1 (0.51) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8409164 | 0.87 | NPC1 (0.35) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8409154 | 0.87 | NPC1 (0.35) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8407971 | 0.86 | NPC1 (0.35) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8406916 | 0.84 | NPC1 (0.50) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL258759 | 0.82 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL31267541 | 0.82 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL29494818 | 0.82 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL14594216 | 0.80 | NPC1 (0.48) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | claimed |
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |