Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.88 |
| ▸ | BCHE | P06276 | 10/20 | 0.88 |
| ▸ | APP | P05067 | 2/20 | 0.88 |
| ▸ | BACE1 | P56817 | 2/20 | 0.88 |
| ▸ | GABRP | O00591 | 1/20 | 0.88 |
| ▸ | GABRD | O14764 | 1/20 | 0.88 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.88 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.88 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.88 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.88 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.88 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.88 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.88 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.88 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.88 |
| ▸ | GABRE | P78334 | 1/20 | 0.88 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.88 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.88 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.88 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38658907 | 1.00 | ACHE (0.88) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL8540965 | 0.95 | BCHE (0.82) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL38658735 | 0.95 | BCHE (0.82) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL24164216 | 0.94 | ACHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL15168191 | 0.94 | ACHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL12059555 | 0.94 | ACHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL29486236 | 0.94 | ACHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| Hydrochloric Acid SCHEMBL29711388 | 0.92 | BCHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL24000133 | 0.92 | BCHE (0.97) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL1532498 | 0.91 | ACHE (0.95) | ACHEBCHEAPPBACE1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065527-A1 | COMPOUDS AND USES AS L-TYPE CALCIUM CHANNEL BLOCKER AND/OR ACETYLCHOLINESTERASE INHIBITOR THEREOF | 江苏先声药物研究有限公司 (CN) | 2012-05-24 | — | — | WO | disclosed |