Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PROC | P04070 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443655 | 0.92 | F10 (0.43) | F10PLGF2PRSS1 | |
| SCHEMBL8440190 | 0.83 | F10 (0.46) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8909375 | 0.81 | F10 (0.53) | F10PLGF2PRSS1 | |
| SCHEMBL7364511 | 0.78 | F10 (0.57) | F10F2PRSS1 | |
| SCHEMBL8908041 | 0.77 | F10 (0.53) | F10F2PRSS1 | |
| SCHEMBL7366139 | 0.77 | F10 (0.53) | F10PLGF2PRSS1 | |
| SCHEMBL7360668 | 0.75 | F2 (0.54) | F10PLGF2PRSS1 | |
| SCHEMBL8483349 | 0.75 | F2 (0.43) | F10PLGF2PRSS1 | |
| SCHEMBL8443278 | 0.74 | F10 (0.52) | F10F2PRSS1 | |
| SCHEMBL8909337 | 0.72 | F10 (0.51) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863914-A | ADMINISTERING TO HUMAN N,N-DIMETHYLBENZENE OR N,N-DIMETHYLNAPHTHALENE-CYCLIC UREA DERIVATIVE TO TREAT A DISEASE-STATE CAUSED BY INHIBITION OF FACTOR XA | MOHAN RAJU (US) | 1999-01-26 | — | — | US | disclosed |
| US-5731308-A | N,N-di(aryl) cyclic urea derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-03-24 | — | — | US | disclosed |
| US-5728697-A | INHIBITORS OF FACTOR X | BERLEX LABORATORIES, INC. (US) | 1998-03-17 | — | — | US | disclosed |
| US-5726173-A | ANTICOAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-03-10 | — | — | US | disclosed |