Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 10/20 | 0.49 |
| ▸ | PLAT | P00750 | 4/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520757 | 0.90 | KMT2A (0.51) | PLAUPLATNR1H4PLGF10 | |
| SCHEMBL7505498 | 0.76 | KMT2A (0.57) | PLAUPLATPLGPOLBITGB3 | |
| SCHEMBL7505503 | 0.76 | KMT2A (0.57) | PLAUPLATPLGPOLBITGB3 | |
| SCHEMBL7503148 | 0.74 | KMT2A (0.55) | PLAUPLATPLGPOLBITGB3 | |
| SCHEMBL7503147 | 0.74 | KMT2A (0.55) | PLAUPLATPLGPOLBITGB3 | |
| SCHEMBL7499925 | 0.74 | LMNA (0.47) | F10 | |
| SCHEMBL27760395 | 0.74 | PTPN1 (0.76) | PLAUNR1H4F2RCCNCCDK8 | |
| SCHEMBL27113200 | 0.71 | CYP3A4 (0.54) | POLBCYP3A4 | |
| SCHEMBL8745242 | 0.71 | PTPN1 (0.77) | PLAUNR1H4F2RCCNCCDK8 | |
| SCHEMBL8520753 | 0.70 | KMT2A (0.48) | PLAUPLATNR1H4PLGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-02-03 | — | — | EP | claimed |
| WO-1997036860-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |