Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6391713 | 0.88 | PYCR1 (0.50) | PYCR1ALDH1A1HRH3LSSTSHR | |
| SCHEMBL3285070 | 0.86 | PYCR1 (0.46) | PYCR1ALDH1A1HRH3LSSTSHR | |
| SCHEMBL18868383 | 0.86 | PYCR1 (0.48) | PYCR1ALDH1A1HRH3LSSTSHR | |
| SCHEMBL18868390 | 0.81 | SIGMAR1 (0.44) | PYCR1ALDH1A1MAOBBCHEACHE | |
| SCHEMBL17409806 | 0.81 | BCHE (0.49) | PYCR1ALDH1A1HRH3TSHRMAOB | |
| SCHEMBL18874552 | 0.79 | ALDH1A1 (0.50) | PYCR1ALDH1A1HRH3TSHRHDAC8 | |
| SCHEMBL465236 | 0.79 | HRH3 (0.56) | PYCR1ALDH1A1HRH3TSHRHDAC8 | |
| SCHEMBL18868380 | 0.79 | PYCR1 (0.43) | PYCR1ALDH1A1HRH3LSSTSHR | |
| SCHEMBL9679480 | 0.79 | PYCR1 (0.43) | PYCR1ALDH1A1HRH3TSHRHDAC3 | |
| Trimethylammonium SCHEMBL2135750 | 0.78 | ALDH1A1 (0.48) | PYCR1ALDH1A1TSHRHDAC8CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858892-A | LARGE REFRACTIVE INDEX DIFFERENCE AND A STABILIZED REFRACTIVE INDEX DISTRIBUTION | OLYMPUS OPTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |