Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 7/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851309 | 0.87 | ST14 (0.55) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3792937 | 0.77 | CA1 (0.45) | SOS1CA12CA1CA2CA9 | |
| SCHEMBL3790590 | 0.76 | ST14 (0.43) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL852134 | 0.72 | ST14 (0.76) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL4038506 | 0.70 | HDAC1 (0.39) | F10CA12CA1CA2CA9 | |
| SCHEMBL3786207 | 0.69 | ST14 (0.67) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3793330 | 0.69 | ST14 (0.71) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL30039108 | 0.67 | PTGS1 (0.47) | F10CA12CA1CA2CA9 | |
| SCHEMBL8508906 | 0.66 | PRSS1 (0.65) | ST14PRSS1PRSS2PRSS3F2 | |
| Hydrochloric Acid SCHEMBL5797803 | 0.66 | PTGS2 (0.54) | CA12CA1CA2CA9PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |