Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.76 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.76 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.76 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.76 |
| ▸ | F2 | P00734 | 3/20 | 0.76 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 5/20 | 0.47 |
| ▸ | MMP13 | P45452 | 5/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508906 | 0.92 | PRSS1 (0.65) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851310 | 0.86 | ST14 (1.00) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3790598 | 0.85 | PRSS1 (0.78) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8510004 | 0.81 | PRSS1 (0.55) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3792939 | 0.76 | F2 (0.62) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3792439 | 0.76 | ST14 (0.77) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL16592750 | 0.74 | LMNA (0.51) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL15705237 | 0.74 | FFAR1 (0.68) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL14645482 | 0.73 | TMPRSS6 (0.69) | — | |
| SCHEMBL852133 | 0.72 | ST14 (0.44) | ST14PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |