Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445210 | 0.80 | HTT (0.55) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL18134021 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8322697 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL8446890 | 0.77 | RORC (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL8445302 | 0.77 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL12916012 | 0.73 | MAPT (0.62) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16404808 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL8799965 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL8699013 | 0.72 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL8521228 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656202-B1 | Dyeing composition containing sulphurous p-phenylene-diamines, sulphurous p-phenylenediamines and method of preparation | OREAL (FR) | 1999-05-06 | — | — | EP | disclosed |
| US-5542952-A | DEVELOPERS THAT FORM STABLE OXIDATION HAIR DYES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |
| EP-0656202-A1 | Dyeing composition containing sulphurous p-phenylene-diamines, novel sulphurous p-phenylenediamines and method of preparation | L'OREAL (FR) | 1995-06-07 | — | — | EP | disclosed |