Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965877 | 0.93 | CNR1 (0.44) | ADAMTS5MMP13CNR1PTPN1HPGD | |
| SCHEMBL8580564 | 0.81 | XDH (0.46) | XDHADAMTS5MMP13CNR1IDH1 | |
| SCHEMBL6967081 | 0.79 | MEN1 (0.38) | PTPN1MEN1KMT2A | |
| SCHEMBL7829571 | 0.74 | HPGD (0.57) | MMP13PTPN1HPGDPOLBMAOA | |
| SCHEMBL13256853 | 0.74 | HPGD (0.57) | MMP13PTPN1HPGDPOLBMAOA | |
| SCHEMBL6978665 | 0.74 | CNR1 (0.43) | XDHADAMTS5MMP13CNR1IDH1 | |
| SCHEMBL6978669 | 0.74 | CNR1 (0.43) | XDHADAMTS5MMP13CNR1IDH1 | |
| SCHEMBL15421425 | 0.72 | ADAMTS5 (0.76) | XDHADAMTS5MMP13CNR1IDH1 | |
| SCHEMBL15421423 | 0.72 | ADAMTS5 (0.76) | XDHADAMTS5MMP13CNR1IDH1 | |
| SCHEMBL6966545 | 0.71 | HPGD (0.52) | MMP13PTPN1HPGDPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894089-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997041121-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |