Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | GPR18 | Q14330 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978665 | 0.94 | CNR1 (0.43) | XDHADAMTS5MMP13GPR119FAAH | |
| SCHEMBL6978669 | 0.94 | CNR1 (0.43) | XDHADAMTS5MMP13GPR119FAAH | |
| SCHEMBL6970447 | 0.88 | HPGD (0.47) | MMP13GPR119MEN1KMT2APTPN1 | |
| SCHEMBL6975793 | 0.88 | HPGD (0.47) | MMP13GPR119MEN1KMT2APTPN1 | |
| SCHEMBL6975305 | 0.88 | HPGD (0.47) | MMP13GPR119MEN1KMT2APTPN1 | |
| SCHEMBL6975790 | 0.88 | HPGD (0.47) | MMP13GPR119MEN1KMT2APTPN1 | |
| SCHEMBL6976209 | 0.87 | FAAH (0.42) | FAAHKCNH2MCHR1 | |
| SCHEMBL6976212 | 0.87 | FAAH (0.42) | FAAHKCNH2MCHR1 | |
| SCHEMBL8522115 | 0.81 | XDH (0.45) | XDHADAMTS5MMP13GPR119IDH1 | |
| SCHEMBL6964226 | 0.81 | KCNH2 (0.38) | FAAHMEN1KMT2AKCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894089-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997041121-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |