Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | S100B | P04271 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186192 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4L3MBTL1TSHR | |
| SCHEMBL3677213 | 0.79 | CYP3A4 (0.46) | ALDH1A1TDP1CYP3A4L3MBTL1TSHR | |
| Sulfurous Acid SCHEMBL11524062 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP3A4L3MBTL1TSHR | |
| Sulfuric Acid SCHEMBL7809539 | 0.75 | ALDH1A1 (0.49) | ALDH1A1TDP1CYP3A4L3MBTL1TSHR | |
| SCHEMBL1341419 | 0.75 | S100B (0.50) | ALDH1A1TDP1CYP3A4L3MBTL1TSHR | |
| SCHEMBL1245943 | 0.75 | CYP3A4 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL8526892 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP3A4L3MBTL1TSHR | |
| SCHEMBL2155334 | 0.74 | ALDH1A1 (0.86) | ALDH1A1TDP1CYP3A4L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL27845061 | 0.73 | S100B (0.48) | ALDH1A1TDP1CYP3A4L3MBTL1TSHR | |
| SCHEMBL30702660 | 0.73 | MAPT (0.47) | ALDH1A1TDP1CYP3A4S100BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625195-B1 | THERAPY OF CENTRAL NERVOUS SYSTEM BY GENETICALLY MODIFIED CELLS | UNIV CALIFORNIA (US) | 1999-01-07 | — | — | EP | disclosed |
| EP-0491057-B1 | HYBRIDOMA WHICH PRODUCES AVIAN SPECIFIC IMMUNOGLOBULIN G | NIPPON KOKAN KK (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5762926-A | Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-06-09 | — | — | US | disclosed |
| US-5650148-A | Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0737743-A1 | Thymidine kinase-lacking ouabain-resistant chicken hybridoma | NKK CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0625195-A1 | THERAPY OF CENTRAL NERVOUS SYSTEM BY GENETICALLY MODIFIED CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993010234-A1 | THERAPY OF CENTRAL NERVOUS SYSTEM BY GENETICALLY MODIFIED CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-05-27 | — | — | WO | disclosed |
| EP-0491057-A1 | HYBRIDOMA WHICH PRODUCES AVIAN SPECIFIC IMMUNOGLOBULIN G | NKK CORPORATION (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-5095094-A | A43 kDa antigenic protein of Bordetella recognized by polyclonal antibodies to adenylate cyclase but devoid of calmodulin-activatable adenylate cyclase activity | INSTITUT PASTEUR (FR) | 1992-03-10 | — | — | US | disclosed |
| EP-0338170-A1 | Immunoprotective antigenic protein against pathogenic bacteria | INSTITUT PASTEUR (FR) | 1989-10-25 | — | — | EP | disclosed |