Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 6/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677212 | 0.79 | CYP3A4 (0.43) | ALDH1A1CYP3A4TDP1TSHRMAPK1 | |
| SCHEMBL7596728 | 0.77 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CYP3A4TDP1RECQL | |
| SCHEMBL2787924 | 0.77 | ALDH1A1 (0.32) | ALDH1A1CYP3A4TDP1MAPTKDM4E | |
| SCHEMBL27593668 | 0.77 | CYP3A4 (0.41) | ALDH1A1CYP3A4TDP1TSHRMAPK1 | |
| SCHEMBL5186192 | 0.76 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CYP3A4TDP1RECQL | |
| SCHEMBL12850053 | 0.75 | PGR (0.47) | ALDH1A1L3MBTL1CYP3A4TDP1RECQL | |
| SCHEMBL15263534 | 0.75 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CYP3A4TDP1RECQL | |
| SCHEMBL16559082 | 0.74 | PGR (0.49) | ALDH1A1L3MBTL1TDP1MAPK1PGR | |
| SCHEMBL8522281 | 0.74 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CYP3A4TDP1RECQL | |
| SCHEMBL20144742 | 0.73 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP3A4TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491057-B1 | HYBRIDOMA WHICH PRODUCES AVIAN SPECIFIC IMMUNOGLOBULIN G | NIPPON KOKAN KK (JP) | 1998-12-30 | — | — | EP | disclosed |
| EP-0737743-A1 | Thymidine kinase-lacking ouabain-resistant chicken hybridoma | NKK CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0491057-A1 | HYBRIDOMA WHICH PRODUCES AVIAN SPECIFIC IMMUNOGLOBULIN G | NKK CORPORATION (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-5095094-A | A43 kDa antigenic protein of Bordetella recognized by polyclonal antibodies to adenylate cyclase but devoid of calmodulin-activatable adenylate cyclase activity | INSTITUT PASTEUR (FR) | 1992-03-10 | — | — | US | disclosed |
| EP-0338170-A1 | Immunoprotective antigenic protein against pathogenic bacteria | INSTITUT PASTEUR (FR) | 1989-10-25 | — | — | EP | disclosed |