Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481854 | 0.68 | CHKA (0.37) | MAPTHRH4ALDH1A1 | |
| SCHEMBL4625323 | 0.66 | DRD2 (0.38) | MAPTHRH4ALDH1A1 | |
| SCHEMBL4777740 | 0.65 | POLB (0.32) | — | |
| SCHEMBL4808079 | 0.65 | ALDH1A1 (0.32) | ALDH1A1 | |
| Ethane SCHEMBL27638639 | 0.64 | — | — | |
| SCHEMBL21275246 | 0.61 | SIRT6 (0.69) | SIRT6LMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL2016171 | 0.61 | SIRT6 (0.69) | SIRT6LMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL447471 | 0.61 | SIRT6 (1.00) | SIRT6LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15557229 | 0.61 | GAA (0.32) | — | |
| SCHEMBL30912575 | 0.59 | SIRT6 (0.59) | SIRT6LMNAMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934937-A1 | Azole derivatives as superoxide radical inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |