Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344630 | 0.78 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6342302 | 0.75 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6344480 | 0.75 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6351545 | 0.73 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6344115 | 0.73 | PTGS2 (0.73) | PTGS2 | |
| SCHEMBL6344539 | 0.72 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL8308620 | 0.72 | SCD (0.55) | PTGS2 | |
| SCHEMBL8573911 | 0.72 | PTGS2 (0.50) | PTGS2KIT | |
| SCHEMBL6351573 | 0.72 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6350326 | 0.72 | PTGS2 (1.00) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915848-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005639-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1998-02-12 | — | — | WO | disclosed |