Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.55 |
| ▸ | FADS1 | O60427 | 1/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444391 | 0.81 | CDK5 (0.55) | CDK5CDK5R1PTGS2CA12CA1 | |
| SCHEMBL8306238 | 0.81 | CDK5 (0.60) | SCDCDK5CDK5R1PTGS2CA12 | |
| SCHEMBL8305443 | 0.80 | CA12 (0.72) | CDK5CDK5R1PTGS2CA12CA1 | |
| SCHEMBL9206986 | 0.78 | PTGS2 (0.73) | SCDFADS1PTGS2 | |
| SCHEMBL8306286 | 0.77 | CDK5 (0.56) | CDK5CDK5R1PTGS2CA12CA1 | |
| SCHEMBL8308055 | 0.76 | MEN1 (0.60) | CDK5CDK5R1PTGS2CA12CA1 | |
| SCHEMBL1460085 | 0.75 | KIF11 (0.42) | SCDFADS1CDK5CDK5R1PTGS2 | |
| SCHEMBL8307211 | 0.75 | CA12 (0.57) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL4154662 | 0.73 | FFAR1 (0.54) | SCDFADS1CA12CA1CA2 | |
| SCHEMBL8522642 | 0.72 | PTGS2 (0.63) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915848-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1999-05-19 | — | — | EP | claimed |
| WO-1998005639-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1998-02-12 | — | — | WO | claimed |