Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | BAD | Q92934 | 1/20 | 0.30 |
| ▸ | HNF4A | P41235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428471 | 0.81 | RARB (0.38) | RARBRARARARGERN1RXRA | |
| SCHEMBL8522832 | 0.74 | RARB (0.52) | RARBRARARARGKDM4EALDH1A1 | |
| SCHEMBL891695 | 0.67 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL728576 | 0.67 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL357341 | 0.67 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL11130591 | 0.66 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHSD17B10HNF4A | |
| SCHEMBL11130587 | 0.66 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHSD17B10HNF4A | |
| SCHEMBL27104316 | 0.66 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4556202 | 0.65 | G6PD (0.52) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7160568 | 0.65 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050142165-A1 | Implant device with a retinoid for improved biocompatibility | OLEJNIK OREST (US) | 2005-06-30 | — | — | US | disclosed |
| US-6743437-B2 | Implant device with a retinoid for improved biocompatibility | ALLERGAN, INC. | 2004-06-01 | — | — | US | disclosed |