Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522687 | 0.82 | ACHE (0.52) | ACHELMNA | |
| SCHEMBL3847058 | 0.78 | SIGMAR1 (0.72) | CHRM3MEN1KMT2A | |
| SCHEMBL29463795 | 0.78 | SIGMAR1 (0.72) | CHRM3MEN1KMT2A | |
| SCHEMBL8294656 | 0.78 | CHRM3 (0.56) | CHRM3 | |
| Hydrochloric Acid SCHEMBL7422123 | 0.77 | SIGMAR1 (0.70) | CHRM3MEN1KMT2A | |
| SCHEMBL1382022 | 0.77 | SIGMAR1 (0.70) | CHRM3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5570576 | 0.77 | CHRM3 (0.55) | CHRM3 | |
| SCHEMBL8523499 | 0.75 | ACHE (0.70) | ACHELMNABCHEMEN1KMT2A | |
| SCHEMBL7649187 | 0.74 | ALDH1A1 (0.69) | CHRM3LMNAMEN1KMT2A | |
| SCHEMBL8523501 | 0.74 | ACHE (0.68) | ACHELMNABCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065527-A1 | COMPOUDS AND USES AS L-TYPE CALCIUM CHANNEL BLOCKER AND/OR ACETYLCHOLINESTERASE INHIBITOR THEREOF | 江苏先声药物研究有限公司 (CN) | 2012-05-24 | — | — | WO | disclosed |