Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.81 |
| ▸ | BCHE | P06276 | 4/20 | 0.81 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.75 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.73 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.73 |
| ▸ | HRH2 | P25021 | 1/20 | 0.72 |
| ▸ | HRH1 | P35367 | 1/20 | 0.72 |
| ▸ | RAD52 | P43351 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15167949 | 0.90 | ACHE (1.00) | ACHEBCHEHRH3HRH2HRH1 | |
| SCHEMBL5945394 | 0.89 | ACHE (0.77) | ACHEBCHEHRH3PABPC1EIF4H | |
| SCHEMBL8522924 | 0.89 | ACHE (0.77) | ACHEBCHEHRH3PABPC1EIF4H | |
| SCHEMBL8523735 | 0.85 | BCHE (0.78) | ACHEBCHE | |
| SCHEMBL15155397 | 0.85 | BCHE (0.96) | ACHEBCHEHRH3HRH2HRH1 | |
| SCHEMBL15168221 | 0.85 | BCHE (0.96) | ACHEBCHEHRH3HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL31087706 | 0.83 | PABPC1 (0.97) | ACHEBCHEHRH3PABPC1EIF4H | |
| SCHEMBL38658735 | 0.83 | BCHE (0.82) | ACHEBCHE | |
| SCHEMBL8540965 | 0.83 | BCHE (0.82) | ACHEBCHE | |
| SCHEMBL1532467 | 0.83 | ACHE (0.69) | ACHEBCHEHRH3PABPC1EIF4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065527-A1 | COMPOUDS AND USES AS L-TYPE CALCIUM CHANNEL BLOCKER AND/OR ACETYLCHOLINESTERASE INHIBITOR THEREOF | 江苏先声药物研究有限公司 (CN) | 2012-05-24 | — | — | WO | disclosed |