Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.48 |
| ▸ | CDK9 | P50750 | 4/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.44 |
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
| ▸ | CCND1 | P24385 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577374 | 0.81 | CCNE2 (0.51) | CCNT1CDK9PIM1CDK2CCNE2 | |
| SCHEMBL8482608 | 0.77 | PRKCA (0.53) | CCNT1CDK9PIM1CDK2CCNE2 | |
| SCHEMBL8482790 | 0.76 | CCNT1 (0.54) | CCNT1CDK9PIM1CDK2CCNE2 | |
| SCHEMBL6999914 | 0.68 | KDR (0.53) | PRKACAPRKACGPRKACBKDM4ENPC1 | |
| SCHEMBL8477326 | 0.68 | GSK3B (0.40) | CCNT1CDK9PIM1PRKACAKDM4E | |
| SCHEMBL8466346 | 0.67 | PRKCA (0.46) | CCNT1CDK9PIM1ALDH1A1LMNA | |
| SCHEMBL8467098 | 0.67 | GSK3B (0.41) | CCNT1CDK9PIM1PRKACAKDM4E | |
| SCHEMBL7195024 | 0.67 | CCNT1 (0.76) | CCNT1CDK9PIM1CDK2CCNE2 | |
| SCHEMBL7506853 | 0.66 | CHEK1 (0.53) | PRKACAPRKACGPRKACBKDM4ENPC1 | |
| SCHEMBL8920197 | 0.65 | CCNT1 (0.66) | CCNT1CDK9PIM1CDK2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| US-5883114-A | TREATING CANCEROUS TUMORS, INFLAMMATORY DISEASES, AND ALLERGIES | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |