Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.51 |
| ▸ | CDK4 | P11802 | 2/20 | 0.51 |
| ▸ | CCND1 | P24385 | 2/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.50 |
| ▸ | CDK9 | P50750 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | PRKACG | P22612 | 1/20 | 0.48 |
| ▸ | PRKACB | P22694 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523455 | 0.81 | CCNT1 (0.48) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8086286 | 0.79 | KDR (0.58) | PRKACAPRKACGPRKACBKDM4ENPC1 | |
| SCHEMBL8161267 | 0.78 | CDK2 (0.56) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL7831969 | 0.78 | PRKACA (0.77) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8482608 | 0.77 | PRKCA (0.53) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8482790 | 0.76 | CCNT1 (0.54) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8161370 | 0.74 | CCNT1 (0.56) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8160875 | 0.74 | CCNT1 (0.56) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8161741 | 0.74 | PRKCA (0.56) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8162060 | 0.73 | CDK2 (0.56) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011105-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | disclosed |