Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.66 |
| ▸ | CDK9 | P50750 | 2/20 | 0.66 |
| ▸ | PIM1 | P11309 | 1/20 | 0.66 |
| ▸ | CAMK2D | Q13557 | 8/20 | 0.66 |
| ▸ | PRKCG | P05129 | 6/20 | 0.66 |
| ▸ | PRKCB | P05771 | 6/20 | 0.66 |
| ▸ | PRKCA | P17252 | 6/20 | 0.66 |
| ▸ | PRKCH | P24723 | 6/20 | 0.66 |
| ▸ | PRKCE | Q02156 | 6/20 | 0.66 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.66 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.66 |
| ▸ | CAMK2B | Q13554 | 6/20 | 0.66 |
| ▸ | CAMK2G | Q13555 | 6/20 | 0.66 |
| ▸ | CAMK2A | Q9UQM7 | 6/20 | 0.66 |
| ▸ | SRC | P12931 | 3/20 | 0.66 |
| ▸ | PRKACA | P17612 | 5/20 | 0.62 |
| ▸ | PRKACG | P22612 | 5/20 | 0.62 |
| ▸ | PRKACB | P22694 | 5/20 | 0.62 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.62 |
| ▸ | CDK4 | P11802 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920763 | 0.90 | CCNT1 (0.61) | CCNT1CDK9PIM1CAMK2DPRKCG | |
| SCHEMBL8921039 | 0.88 | CAMK2D (0.61) | CCNT1CDK9PIM1CAMK2DPRKCG | |
| SCHEMBL7195523 | 0.82 | CCNT1 (0.81) | CCNT1CDK9PIM1CAMK2DPRKCG | |
| SCHEMBL30834685 | 0.78 | CCNT1 (0.74) | CCNT1CDK9PIM1CAMK2DPRKCG | |
| SCHEMBL7822250 | 0.77 | CDK4 (1.00) | CCNT1CDK9PIM1CAMK2DPRKCG | |
| SCHEMBL7831969 | 0.77 | PRKACA (0.77) | CCNT1CDK9PIM1CAMK2DPRKCG | |
| SCHEMBL18392163 | 0.75 | CDK4 (0.68) | CCNT1CDK9PIM1CAMK2DPRKCG | |
| SCHEMBL8482614 | 0.73 | PIM1 (0.66) | CCNT1CDK9PIM1CAMK2DPRKCG | |
| SCHEMBL3146547 | 0.73 | PRKCB (1.00) | CDK9PIM1CAMK2DPRKCGPRKCB | |
| SCHEMBL8482796 | 0.72 | CCNT1 (0.65) | CCNT1CDK9PIM1CAMK2DPRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672618-A | TREATING DIABETIC COMPLICATIONS | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |