Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7325842 | 0.99 | LMNA (0.51) | LMNAGRIN1GRIN2BSLC18A3CHRM2 | |
| SCHEMBL8333036 | 0.84 | MEN1 (0.41) | LMNAGRIN1GRIN2BSLC18A3CHRM2 | |
| Hydrochloric Acid SCHEMBL7325272 | 0.83 | MEN1 (0.42) | LMNAGRIN1GRIN2BSLC18A3CHRM2 | |
| SCHEMBL10476961 | 0.77 | APP (0.48) | LMNASLC18A3SIGMAR1MEN1KMT2A | |
| SCHEMBL22485567 | 0.76 | DRD2 (0.58) | SLC18A3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6972319 | 0.75 | HRH3 (0.65) | GRIN2BSLC18A3SIGMAR1DRD2MEN1 | |
| SCHEMBL5730065 | 0.75 | LMNA (0.78) | LMNAGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL5726911 | 0.75 | PPARG (0.57) | LMNAGRIN1GRIN2BSLC18A3 | |
| SCHEMBL5726903 | 0.75 | PPARG (0.57) | LMNAGRIN1GRIN2BSLC18A3 | |
| SCHEMBL12319790 | 0.74 | DRD2 (0.55) | SLC18A3SIGMAR1DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154483-C | Use of amines to produce drugs for preventing tumour cell proliferation | ��ŵ��-ʥ�������ɷ�����˾ | 2004-06-23 | — | — | CN | disclosed |
| CN-1226825-A | Use of amines to produce drugs for preventing tumour cell proliferation | SANOFI SA (FR) | 1999-08-25 | — | — | CN | disclosed |
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |