Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TNNI3K | Q59H18 | 7/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720743 | 0.88 | SIGMAR1 (0.48) | SIGMAR1LMNAL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL8556316 | 0.80 | POLB (0.51) | LMNAPTBP1L3MBTL1TNNI3KRAB9A | |
| SCHEMBL6719248 | 0.76 | SIGMAR1 (0.50) | SIGMAR1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL6725035 | 0.76 | SIGMAR1 (0.62) | SIGMAR1LMNAL3MBTL1TDP1MEN1 | |
| SCHEMBL6720634 | 0.75 | MEN1 (0.51) | SIGMAR1LMNAL3MBTL1TDP1RAB9A | |
| Hydrochloric Acid SCHEMBL7410846 | 0.75 | SIGMAR1 (0.60) | SIGMAR1LMNAL3MBTL1TDP1MEN1 | |
| SCHEMBL6724149 | 0.74 | SIGMAR1 (0.48) | SIGMAR1LMNARAB9AALDH1A1MEN1 | |
| SCHEMBL6720746 | 0.73 | SIGMAR1 (0.47) | SIGMAR1L3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL4151992 | 0.73 | LMNA (0.52) | LMNAPTBP1TNNI3KEGFRBRAF | |
| SCHEMBL8337122 | 0.72 | SIGMAR1 (0.49) | SIGMAR1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |