Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667926 | 0.89 | MEN1 (0.37) | KMT2AMEN1POLBTP53GAA | |
| Hydrochloric Acid SCHEMBL8663917 | 0.88 | MEN1 (0.36) | KMT2AMEN1POLBTP53GAA | |
| SCHEMBL8501146 | 0.88 | POLB (0.35) | KMT2AMEN1POLBDRD2DRD4 | |
| SCHEMBL8662751 | 0.87 | KMT2A (0.35) | KMT2AMEN1POLBBCHESSTR2 | |
| SCHEMBL8504394 | 0.87 | MEN1 (0.37) | KMT2AMEN1POLBTP53GAA | |
| SCHEMBL8503676 | 0.87 | POLB (0.35) | POLBALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL8523535 | 0.85 | KMT2A (0.40) | KMT2AMEN1POLBALDH1A1BRPF1 | |
| SCHEMBL8667146 | 0.81 | RXFP1 (0.34) | KMT2AMEN1GAA | |
| SCHEMBL8593680 | 0.81 | POLB (0.42) | KMT2APOLBALDH1A1DRD2DRD4 | |
| SCHEMBL8500999 | 0.80 | CTSL (0.37) | POLBALDH1A1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | claimed |