Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865964 | 1.00 | THRB (0.34) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL7516301 | 0.82 | CA1 (0.41) | THRBRECQLTDP1MEN1POLB | |
| SCHEMBL8523627 | 0.81 | TDP1 (0.43) | THRBTDP1MAPTPKMALDH1A1 | |
| SCHEMBL6278830 | 0.78 | CASP1 (0.32) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL646259 | 0.75 | CYP3A4 (0.38) | TDP1MEN1MAPTKMT2ACASP1 | |
| SCHEMBL8675177 | 0.73 | KDM4E (0.39) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29940754 | 0.72 | ALDH1A1 (0.41) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL446559 | 0.72 | ALDH1A1 (0.41) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL29358097 | 0.71 | THRB (0.36) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL11584910 | 0.71 | CASP1 (0.38) | THRBRECQLTDP1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306179-B1 | FOR DYEING HAIR | L'OREAL S.A. (FR) | 2001-10-23 | — | — | US | claimed |
| EP-0911317-B1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | OREAL (FR) | 2000-09-13 | — | — | EP | claimed |
| US-4840639-A | OXIDATIVE DYEING; MIXTURE WITH COUPLER AND DEVELOPER | WELLA AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| WO-1980000214-A1 | PREPARATION FOR HAIR COLORATION | WELLA AG (DE) | 1980-02-21 | — | — | WO | claimed |
| EP-0007537-A1 | Hair dyeing composition | Wella Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | claimed |
| EP-2678079-B1 | OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A BENZO[1,3]DIOXOL-5-YLAMINE AND DERIVATIVES THEREOF | NOXELL CORP (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-0891765-B1 | Oxidative hair dye compositions | P & G CLAIROL INC (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6554870-B1 | E.g.,(2-hydroxyethyl)-para-phenylenediamine; e.g, copolymers of diallyldimethylammonium chloride and acrylamide or acrylic acid, and quaternized polyamines and polyaminoamides | L'OREAL (FR) | 2003-04-29 | — | — | US | disclosed |
| US-6306179-B1 | FOR DYEING HAIR | L'OREAL S.A. (FR) | 2001-10-23 | — | — | US | disclosed |
| US-6306179-B1 | FOR DYEING HAIR | L'OREAL S.A. (FR) | 2001-10-23 | — | — | US | disclosed |
| US-6306179-B1 | FOR DYEING HAIR | L'OREAL S.A. (FR) | 2001-10-23 | — | — | US | disclosed |
| EP-0891765-A2 | Oxidative hair dye compositions | Bristol-Myers Squibb Company (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5851237-A | Oxidative hair dye compositions and methods containing 1--(4-aminophenyl) pyrrolidines | NOXELL CORPORATION | 1998-12-22 | — | — | US | disclosed |
| US-5735908-A | HAIR DYES WITH COUPLERS | L'OREAL (FR) | 1998-04-07 | — | — | US | disclosed |
| EP-0667142-B1 | Oxidation dyeing composition for keratinic fibers comprising a paraphenylenediamine derivative and 2-methyl-5-aminophenol and method using such a composition | OREAL (FR) | 1997-06-18 | — | — | EP | disclosed |
| US-4840639-A | OXIDATIVE DYEING; MIXTURE WITH COUPLER AND DEVELOPER | WELLA AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| US-4840639-A | OXIDATIVE DYEING; MIXTURE WITH COUPLER AND DEVELOPER | WELLA AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| WO-1980000214-A1 | PREPARATION FOR HAIR COLORATION | WELLA AG (DE) | 1980-02-21 | — | — | WO | disclosed |
| EP-0007537-A1 | Hair dyeing composition | Wella Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |
| EP-0007537-A1 | Hair dyeing composition | Wella Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |