Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523101 | 0.91 | HSP90AA1 (0.34) | HSP90AA1 | |
| SCHEMBL9288292 | 0.90 | HSP90AA1 (0.43) | S1PR1S1PR3HSP90AA1S1PR4S1PR5 | |
| SCHEMBL4319042 | 0.72 | HSP90AA1 (0.41) | HSP90AA1 | |
| SCHEMBL49211 | 0.71 | HSP90AA1 (0.53) | HSP90AA1 | |
| SCHEMBL4307871 | 0.68 | HSP90AA1 (0.53) | HSP90AA1 | |
| SCHEMBL9188392 | 0.68 | HSP90AA1 (0.44) | HSP90AA1 | |
| SCHEMBL49631 | 0.63 | HSP90AA1 (0.46) | HSP90AA1 | |
| SCHEMBL49241 | 0.62 | HSP90AA1 (0.41) | HSP90AA1 | |
| SCHEMBL259402 | 0.62 | HSP90AA1 (0.39) | HSP90AA1 | |
| SCHEMBL14940566 | 0.59 | HSP90AA1 (0.53) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557654-B1 | Polyphenelene ether alloys | GEN ELECTRIC (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5521244-A | MOLDABLE ENGINEERING THERMOPLASTICS | GENERAL ELECTRIC COMPANY (US) | 1996-05-28 | — | — | US | disclosed |
| US-5399610-A | Polymer composition made by reacting a mixture of epoxy functionalized polyphenylene ether, polyester and hydrogenated poly/alpha-olefin/ fluid | GENERAL ELECTRIC COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5376714-A | Containing aluminum salt of a phosphonic acid | GENERAL ELECTRIC COMPANY, A NY CORP. | 1994-12-27 | — | — | US | disclosed |
| EP-0557654-A1 | Polyphenelene ether alloys | GENERAL ELECTRIC COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| EP-0550211-A1 | Flowable polyphenylene ether compositions | GENERAL ELECTRIC COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |
| EP-0501155-A2 | Process for functionalizing polyphenylene ether | GENERAL ELECTRIC COMPANY (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5115043-A | Endcapping | GENERAL ELECTRIC COMPANY (US) | 1992-05-19 | — | — | US | disclosed |