SCHEMBL8523101

SCHEMBL8523101

CCC(CC)(COP(=O)(O)O)Oc1nc(Cl)nc(Oc2c(C)cc(C)cc2C)n1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8523654 0.91 S1PR1 (0.32) HSP90AA1
SCHEMBL5608545 0.84 KMT2A (0.34)
SCHEMBL9288292 0.80 HSP90AA1 (0.43) HSP90AA1
SCHEMBL49211 0.74 HSP90AA1 (0.53) HSP90AA1
SCHEMBL4307871 0.72 HSP90AA1 (0.53) HSP90AA1
SCHEMBL9188392 0.71 HSP90AA1 (0.44) HSP90AA1
SCHEMBL4319042 0.68 HSP90AA1 (0.41) HSP90AA1
SCHEMBL49631 0.67 HSP90AA1 (0.46) HSP90AA1
SCHEMBL49241 0.66 HSP90AA1 (0.41) HSP90AA1
SCHEMBL259402 0.65 HSP90AA1 (0.39) HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0522767-B1 Method for preparing reactive triazine-capped aromatic polymers GEN ELECTRIC (US) 1996-12-18 EP claimed
US-5264496-A Aromatic hydroxy group polymer modified with chlorotriazines and using phase transfer catalyst and tertiary amine for reaction GENERAL ELECTRIC COMPANY (US) 1993-11-23 US claimed
EP-0522767-A2 Method for preparing reactive triazine-capped aromatic polymers GENERAL ELECTRIC COMPANY (US) 1993-01-13 EP claimed
EP-0461433-A2 Substituted chlorotriazines useful for reactive capping of polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1991-12-18 EP claimed
EP-0557654-B1 Polyphenelene ether alloys GEN ELECTRIC (US) 1999-03-31 EP disclosed
EP-0522767-B1 Method for preparing reactive triazine-capped aromatic polymers GEN ELECTRIC (US) 1996-12-18 EP disclosed
US-5521244-A MOLDABLE ENGINEERING THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 1996-05-28 US disclosed
EP-0461434-B1 Substituted triazine-capped polyphenylene ethers GEN ELECTRIC (US) 1995-09-20 EP disclosed
EP-0462410-B1 Copolymer-containing compositions from substituted triazine-capped polyphenylene ethers GEN ELECTRIC (US) 1995-08-23 EP disclosed
US-5399610-A Polymer composition made by reacting a mixture of epoxy functionalized polyphenylene ether, polyester and hydrogenated poly/alpha-olefin/ fluid GENERAL ELECTRIC COMPANY (US) 1995-03-21 US disclosed
US-5376714-A Containing aluminum salt of a phosphonic acid GENERAL ELECTRIC COMPANY, A NY CORP. 1994-12-27 US disclosed
US-5264496-A Aromatic hydroxy group polymer modified with chlorotriazines and using phase transfer catalyst and tertiary amine for reaction GENERAL ELECTRIC COMPANY (US) 1993-11-23 US disclosed
EP-0522767-A2 Method for preparing reactive triazine-capped aromatic polymers GENERAL ELECTRIC COMPANY (US) 1993-01-13 EP disclosed
US-5159075-A Compatibilizers for copolymerization; impact strength GENERAL ELECTRIC COMPANY (US) 1992-10-27 US disclosed
EP-0501155-A2 Process for functionalizing polyphenylene ether GENERAL ELECTRIC COMPANY (US) 1992-09-02 EP disclosed
US-5089567-A Impact strength GENERAL ELECTRIC COMPANY (US) 1992-02-18 US disclosed
EP-0462410-A2 Copolymer-containing compositions from substituted triazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1991-12-27 EP disclosed
EP-0461434-A2 Substituted triazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1991-12-18 EP disclosed
EP-0461433-A2 Substituted chlorotriazines useful for reactive capping of polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1991-12-18 EP disclosed
US-5010144-A Copolymerized with polyesters, polyamides and polyolefns contining nulceophilic groups; impact strength GENERAL ELECTRIC COMPANY (US) 1991-04-23 US disclosed