Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 8/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662384 | 0.88 | FAAH (0.62) | FAAHDAGLA | |
| SCHEMBL1958546 | 0.82 | FAAH (0.54) | FAAHMEN1ALDH1A1MAPTHTT | |
| SCHEMBL28251784 | 0.81 | FAAH (0.56) | FAAHMEN1ALDH1A1MAPTHTT | |
| SCHEMBL5535082 | 0.81 | FAAH (0.56) | FAAHMEN1ALDH1A1MAPTHTT | |
| SCHEMBL1255019 | 0.78 | LMNA (0.61) | CTNNB1WNT3AFAAHALDH1A1HTT | |
| SCHEMBL1254915 | 0.77 | LMNA (0.63) | CTNNB1WNT3AFAAHDAGLAHTT | |
| SCHEMBL9658034 | 0.77 | LMNA (0.63) | CTNNB1WNT3AFAAHDAGLAHTT | |
| SCHEMBL9440127 | 0.77 | LMNA (0.63) | CTNNB1WNT3AFAAHDAGLAHTT | |
| SCHEMBL17817131 | 0.77 | LMNA (0.63) | CTNNB1WNT3AFAAHDAGLAHTT | |
| SCHEMBL1254914 | 0.77 | LMNA (0.63) | CTNNB1WNT3AFAAHDAGLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927169-A1 | 4-CYCLOALKYL-5-SUBSTITUTED PYRIMIDINE COMPOUNDS USEFUL AS CROP PROTECTION AGENTS | ZENECA LIMITED (GB) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011074-A1 | 4-CYCLOALKYL-5-SUBSTITUTED PYRIMIDINE COMPOUNDS USEFUL AS CROP PROTECTION AGENTS | ZENECA LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |