Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | CDC25C | P30307 | 3/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524875 | 0.88 | KDM4E (0.41) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8525097 | 0.79 | CDC25A (0.46) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8483824 | 0.77 | CDC25A (0.56) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8524583 | 0.77 | CDC25A (0.44) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8525207 | 0.77 | KDM4E (0.42) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8524006 | 0.77 | RAB9A (0.44) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8524649 | 0.75 | RARA (0.44) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8525211 | 0.74 | CDC25A (0.43) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8484367 | 0.74 | CDC25A (0.48) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8524425 | 0.71 | KDM4E (0.44) | CDC25ACDC25BCDC25CDUSP3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |