Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720236 | 0.84 | PTPRB (0.42) | TACR1GHSR | |
| SCHEMBL6316892 | 0.84 | TACR1 (0.44) | TACR1MC4RMC3RMC1RGHSR | |
| SCHEMBL6326308 | 0.83 | TACR1 (0.43) | TACR1MC4RMC3RMC1RGHSR | |
| SCHEMBL8905293 | 0.82 | TACR1 (0.43) | TACR1GHSRBDKRB2FCER2 | |
| SCHEMBL6318359 | 0.81 | TACR1 (0.42) | SLC6A2SLC6A4SLC6A3TACR1MC4R | |
| SCHEMBL6316223 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL8711092 | 0.80 | MMP9 (0.47) | TACR1GHSRFCER2 | |
| SCHEMBL8717973 | 0.79 | GHSR (0.43) | GHSRFCER2 | |
| SCHEMBL6319534 | 0.79 | TACR1 (0.43) | TACR1MC4RMC3RMC1RGHSR | |
| SCHEMBL7660423 | 0.79 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833845-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-04-08 | — | — | EP | claimed |
| WO-1998008492-A1 | TRANSDERMAL DELIVERY OF PEPTIDES | NOVO NORDISK A/S (DK) | 1998-03-05 | — | — | WO | claimed |
| WO-1997000894-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | claimed |
| EP-0907374-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998008492-A1 | TRANSDERMAL DELIVERY OF PEPTIDES | NOVO NORDISK A/S (DK) | 1998-03-05 | — | — | WO | disclosed |
| WO-1997046252-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1997-12-11 | — | — | WO | disclosed |