Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523939 | 0.84 | SLC6A2 (0.41) | TACR1GHSR | |
| SCHEMBL8717973 | 0.83 | GHSR (0.43) | GHSRPTPN1 | |
| SCHEMBL6319971 | 0.83 | YAP1 (0.42) | YAP1TACR1STSGHSRUSP30 | |
| SCHEMBL7658396 | 0.82 | YAP1 (0.43) | PTPRBPTPN11YAP1TACR1STS | |
| SCHEMBL7160870 | 0.81 | CTSB (0.42) | TACR1KMT2AGHSR | |
| SCHEMBL6318108 | 0.80 | GHSR (0.46) | YAP1GHSR | |
| SCHEMBL7658402 | 0.79 | PTPRB (0.40) | PTPRBPTPN11YAP1TACR1STS | |
| SCHEMBL6600960 | 0.78 | USP30 (0.41) | PTPRBPTPN11YAP1TACR1STS | |
| SCHEMBL6324706 | 0.78 | GHSR (0.49) | YAP1GHSRUSP30 | |
| SCHEMBL6324711 | 0.78 | GHSR (0.49) | YAP1GHSRUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833845-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000894-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | disclosed |