Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 7/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488625 | 0.89 | NPC1 (0.40) | NPC1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8488306 | 0.88 | SMN1; SMN2 (0.38) | NPC1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8525422 | 0.86 | HCRTR2 (0.35) | NPC1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8488620 | 0.86 | NPC1 (0.35) | NPC1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8491383 | 0.85 | GABRG2 (0.33) | NPC1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8490079 | 0.85 | KDM4E (0.38) | ALDH1A1SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL8491704 | 0.83 | HTT (0.41) | NPC1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8525765 | 0.79 | LMNA (0.34) | ALDH1A1KDM4EHSD17B10LMNARXFP1 | |
| SCHEMBL8524884 | 0.79 | LMNA (0.34) | ALDH1A1KDM4EHSD17B10LMNARXFP1 | |
| SCHEMBL8494652 | 0.78 | NR1H4 (0.39) | NPC1ALDH1A1SMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |