SCHEMBL8524080

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30456979	1.00	AHR (0.62)	AHRCYP3A4MEN1KMT2AIGF1R
	SCHEMBL3526160	0.86	AHR (0.62)	AHRMEN1KMT2AFLT1ALDH1A1
	SCHEMBL30787730	0.82	AHR (0.53)	AHRCYP3A4MEN1KMT2AFLT1
	SCHEMBL1751672	0.82	AHR (0.53)	AHRCYP3A4MEN1KMT2AIGF1R
	SCHEMBL5302174	0.82	AHR (0.53)	AHRCYP3A4MEN1KMT2AFLT1
	SCHEMBL3073324	0.76	MEN1 (0.47)	AHRCYP3A4MEN1KMT2AIGF1R
	SCHEMBL15613033	0.76	CYP3A4 (0.37)	AHRCYP3A4MEN1KMT2AIGF1R
	SCHEMBL15893452	0.73	GAA (0.52)	AHRCYP3A4MEN1KMT2AFLT1
	SCHEMBL4133359	0.73	CYP3A4 (0.38)	AHRCYP3A4MEN1KMT2AFLT1
	SCHEMBL1702010	0.73	AHR (0.47)	AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.