SCHEMBL8524104

SCHEMBL8524104

COC(OC)C(=O)c1cccc(-c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.55
HDAC8 Q9BY41 1/20 0.50
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 2/20 0.46
GAA P10253 1/20 0.46
ERCC5 P28715 2/20 0.46
FEN1 P39748 2/20 0.46
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
HPGD P15428 2/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7995250 0.84 SMN1; SMN2 (0.53) MAPTLMNAGAAHPGDKDM4E
SCHEMBL28197933 0.83 TSHR (0.52) MAPTTDP1LMNAMEN1POLB
SCHEMBL26712 0.83 TSHR (0.52) MAPTTDP1LMNAMEN1POLB
Benzene SCHEMBL27641543 0.83 TSHR (0.52) MAPTTDP1LMNAMEN1POLB
SCHEMBL10276830 0.80 KMO (0.60) KMOHDAC8MAPTTDP1LMNA
SCHEMBL5790150 0.79 RHOA (0.49) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL9719861 0.79 CA12 (0.52) MAPTGAAPOLBKDM4EALDH1A1
SCHEMBL28233138 0.79 PARP1 (0.53) HDAC8TDP1MEN1POLBKMT2A
SCHEMBL14564385 0.78 KMO (0.62) KMOHDAC8MAPTTDP1LMNA
Benzophenone SCHEMBL28320289 0.78 ALDH1A1 (0.56) MAPTTDP1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4994703-A Piezoelectric element of laminate type MITSUBISHI KASEI CORPORATION (JP) 1991-02-19 US claimed
WO-1999010409-A1 RADIATION-POLYMERIZABLE COMPOSITION AND PRINTING INKS CONTAINING SAME HENKEL CORPORATION (US) 1999-03-04 WO disclosed
US-4994703-A Piezoelectric element of laminate type MITSUBISHI KASEI CORPORATION (JP) 1991-02-19 US disclosed