Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101582 | 0.89 | PTGS1 (0.50) | PTGS1PTGS2CCR2CYP2C9SLC6A3 | |
| SCHEMBL8525177 | 0.83 | PTGS1 (0.50) | PTGS1PTGS2CCR2CYP2C9SLC6A3 | |
| SCHEMBL8523577 | 0.81 | PTGS1 (0.58) | PTGS1PTGS2CCR2CYP2C9SLC6A3 | |
| SCHEMBL8524769 | 0.79 | PTGS1 (0.50) | PTGS1PTGS2CCR2CYP2C9SLC6A3 | |
| SCHEMBL8099718 | 0.74 | PTGS1 (0.68) | PTGS1PTGS2CCR2SLC6A3SLC6A4 | |
| SCHEMBL8107162 | 0.74 | PTGS1 (0.61) | PTGS1PTGS2CCR2CYP2C9SLC6A3 | |
| SCHEMBL9657545 | 0.74 | PTGS1 (0.61) | PTGS1PTGS2CCR2SLC6A3SLC6A4 | |
| SCHEMBL11177507 | 0.74 | PTGS2 (0.58) | PTGS1PTGS2CCR2CYP2C9SLC6A3 | |
| SCHEMBL8101589 | 0.74 | PTGS2 (0.61) | PTGS1PTGS2CCR2CYP2C9SLC6A3 | |
| Methylamine SCHEMBL8479365 | 0.74 | PTGS2 (0.58) | PTGS1PTGS2CCR2CYP2C9SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004948-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | NYCOMED AUSTRIA GMBH (AT) | 1999-12-21 | — | — | US | disclosed |