Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | TTR | P02766 | 4/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 7/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CBR1 | P16152 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160901 | 0.85 | FFAR1 (0.60) | PTGS1PTGS2CCR2PTGDRPTGDR2 | |
| SCHEMBL8481368 | 0.84 | PTGS1 (0.52) | PTGS1PTGS2TTRCCR2PTGDR | |
| SCHEMBL7161648 | 0.81 | PTGS1 (0.52) | PTGS1PTGS2CCR2PTGDRPTGDR2 | |
| SCHEMBL8524150 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2TTRCCR2PTGDR | |
| SCHEMBL8099718 | 0.80 | PTGS1 (0.68) | PTGS1PTGS2CCR2LMNAPGR | |
| SCHEMBL7162523 | 0.79 | PTGS1 (0.59) | PTGS1PTGS2TTRCCR2PTGDR | |
| SCHEMBL8524539 | 0.78 | TTR (0.56) | PTGS1PTGS2TTRCCR2PTGDR2 | |
| SCHEMBL8525177 | 0.78 | PTGS1 (0.50) | PTGS1PTGS2TTRCCR2PTGDR | |
| SCHEMBL8099545 | 0.76 | CCR2 (0.56) | PTGS1PTGS2TTRCCR2PTGDR | |
| SCHEMBL13236301 | 0.76 | TTR (0.70) | TTRMRGPRX4NR1I2LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004948-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | NYCOMED AUSTRIA GMBH (AT) | 1999-12-21 | — | — | US | disclosed |