Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 14/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 14/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525207 | 0.87 | KDM4E (0.42) | CDK5CDK5R1KDM4ENPC1RAB9A | |
| SCHEMBL8525334 | 0.82 | CDK5 (0.39) | CDK5CDK5R1KDM4ENPC1RAB9A | |
| SCHEMBL8525110 | 0.78 | CDK5 (0.42) | CDK5CDK5R1KDM4ENPC1RAB9A | |
| SCHEMBL8524649 | 0.77 | RARA (0.44) | CDK5CDK5R1KDM4ENPC1RAB9A | |
| SCHEMBL8524322 | 0.75 | CDC25A (0.49) | CDK5CDK5R1KDM4ENPC1RAB9A | |
| SCHEMBL8524544 | 0.75 | CYP19A1 (0.44) | CDK5CDK5R1KDM4ECYP19A1 | |
| SCHEMBL8523986 | 0.75 | CDK5 (0.40) | CDK5CDK5R1KDM4ENPC1RAB9A | |
| SCHEMBL8524782 | 0.74 | CYP19A1 (0.48) | CDK5CDK5R1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8524583 | 0.73 | CDC25A (0.44) | CDK5CDK5R1KDM4ENPC1RAB9A | |
| SCHEMBL8524156 | 0.73 | CDC25A (0.45) | CDK5CDK5R1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |