Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 3/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | CDC25C | P30307 | 3/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | SREBF2 | Q12772 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525207 | 0.88 | KDM4E (0.42) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524782 | 0.88 | CYP19A1 (0.48) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524913 | 0.85 | CDC25A (0.36) | CDC25ACDC25BCDC25CDUSP3BACE1 | |
| SCHEMBL8525200 | 0.84 | BACE1 (0.35) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8523780 | 0.78 | CYP19A1 (0.48) | CYP19A1CDK5CDK5R1SREBF2MAPT | |
| SCHEMBL8524649 | 0.78 | RARA (0.44) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524244 | 0.75 | CDK5 (0.38) | CYP19A1CDK5CDK5R1KDM4E | |
| SCHEMBL8524322 | 0.75 | CDC25A (0.49) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524583 | 0.74 | CDC25A (0.44) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8485341 | 0.73 | CDC25A (0.43) | CYP19A1CDC25ACDC25BCDC25CDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |