Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | AHCY | P23526 | 9/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PRPS1 | P60891 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524247 | 1.00 | THRB (0.41) | THRBAHCYCYP2C9IDO1KCNH2 | |
| SCHEMBL9119445 | 0.81 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL8525972 | 0.81 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL8525973 | 0.81 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL9120372 | 0.81 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL9120465 | 0.81 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL8659894 | 0.77 | AHCY (0.52) | THRBAHCYCYP2C9IDO1KCNH2 | |
| SCHEMBL8659891 | 0.77 | AHCY (0.52) | THRBAHCYCYP2C9IDO1KCNH2 | |
| SCHEMBL7616161 | 0.75 | PRPS1 (0.48) | THRBKCNH2PRPS1 | |
| SCHEMBL7616155 | 0.75 | PRPS1 (0.48) | THRBKCNH2PRPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912356-A | HERPES VIRUS | GLAXO WELLCOME INC. (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0779885-A1 | ANTIVIRAL NUCLEOSIDE ANALOGUES CONTAINING A SUBSTITUTED BENZIMIDAZOLE BASE ATTACHED TO A CARBOCYCLIC RING | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-06-25 | — | — | EP | disclosed |
| US-5534535-A | ANTIVIRAL ANALOGS WITH SUBSTITUTED BENZIMIDAZOLE BASE | BURROUGHS WELLCOME CO. (US) | 1996-07-09 | — | — | US | disclosed |
| WO-1996007646-A1 | ANTIVIRAL NUCLEOSIDE ANALOGUES CONTAINING A SUBSTITUTED BENZIMIDAZOLE BASE ATTACHED TO A CARBOCYCLIC RING | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-03-14 | — | — | WO | disclosed |