Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | CEL | P19835 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850899 | 0.90 | HRH4 (0.40) | HRH4HRH3DAOLMNATSHR | |
| SCHEMBL7625072 | 0.87 | GPR84 (0.42) | HRH4HRH3CEL | |
| SCHEMBL7621912 | 0.84 | HRH4 (0.32) | HRH4HRH3DAOLMNATSHR | |
| SCHEMBL7069782 | 0.84 | CDK1 (0.33) | HRH4HRH3DAOLMNATSHR | |
| SCHEMBL7069780 | 0.84 | CDK1 (0.33) | HRH4HRH3DAOLMNATSHR | |
| SCHEMBL7069783 | 0.84 | CDK1 (0.33) | HRH4HRH3DAOLMNATSHR | |
| SCHEMBL6353897 | 0.84 | HRH3 (0.49) | HRH4HRH3 | |
| SCHEMBL7971225 | 0.83 | HRH3 (0.40) | HRH4HRH3CDK1CCNB1CCNA2 | |
| SCHEMBL7977147 | 0.83 | HRH4 (0.38) | HRH4HRH3CDK1CCNB1CCNA2 | |
| SCHEMBL7621345 | 0.82 | HRH4 (0.30) | HRH4HRH3LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999006377-A1 | DERIVATIVES OF 1-((3,3-DIMETHYL-3-SILABUTOXY)METHYL)-2-(PHENYLSULFONYL)IMIDAZOLE | GLIATECH, INC. (US) | 1999-02-11 | — | — | WO | disclosed |