Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KDM5C | P41229 | 4/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.52 |
| ▸ | KDM6B | O15054 | 2/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317397 | 0.78 | — | — | |
| SCHEMBL4098641 | 0.78 | PHF8 (0.68) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| Succinic Acid SCHEMBL1071158 | 0.78 | LMNA (0.64) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| Hydrochloric Acid SCHEMBL11532728 | 0.76 | — | — | |
| SCHEMBL1735259 | 0.75 | — | — | |
| SCHEMBL30572348 | 0.75 | PHF8 (0.65) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL17024369 | 0.75 | PHF8 (0.65) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL218098 | 0.75 | PHF8 (0.65) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| Succinic Acid SCHEMBL30862138 | 0.74 | KDM4E (0.59) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| Succinic Acid SCHEMBL28239345 | 0.74 | KDM4E (0.59) | EGLN1KDM4EKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958747-A | NUCLEIC ACID CODING FOR ENZYME IMPORTANT IN HEME BIOSYNTHESIS; FOR PRODUCTION OF HERBICIDES AND TO INCREASE THE YIELD OF HEMOPROTEIN PRODUCED BY HOST CELLS | NOVO NORDISK BIOTECH, INC (US) | 1999-09-28 | — | — | US | disclosed |