Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.68 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.68 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | KDM5C | P41229 | 4/20 | 0.68 |
| ▸ | KDM6B | O15054 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.64 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17024369 | 0.97 | PHF8 (0.65) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL18342669 | 0.91 | PHF8 (0.59) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL218098 | 0.90 | PHF8 (0.65) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL30572348 | 0.90 | PHF8 (0.65) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377429 | 0.87 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377444 | 0.87 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377423 | 0.87 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377438 | 0.87 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| Ammonia Solution, Strong SCHEMBL20377426 | 0.87 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL6914036 | 0.87 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770442-B2 | Self-assembling amphiphilic polymers as anti-cancer agents | ALLEXCEL INC. (US) | 2017-09-26 | — | — | US | disclosed |
| US-8968716-B2 | In situ-forming hydrogel for tissue adhesives and biomedical use thereof | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-03-03 | — | — | US | disclosed |
| US-8815277-B2 | In situ forming hydrogel and biomedical use thereof | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2014-08-26 | — | — | US | disclosed |
| US-8791211-B2 | High refractive polymers, optical elements, and photoelectric device employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2014-07-29 | — | — | US | disclosed |
| US-20130224795-A1 | IMMOBILIZATION METHOD OF BIOACTIVE MOLECULES USING POLYPHENOL OXIDASE | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2013-08-29 | — | — | US | disclosed |
| US-20120197000-A1 | HIGH REFRACTIVE POLYMERS, OPTICAL ELEMENTS, AND PHOTOELECTRIC DEVICE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-08-02 | — | — | US | disclosed |
| US-20120156164-A1 | IN SITU-FORMING HYDROGEL FOR TISSUE ADHESIVES AND BIOMEDICAL USE THEREOF | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2012-06-21 | — | — | US | disclosed |
| US-8173764-B2 | Solubilization and targeted delivery of drugs with self-assembling amphiphilic polymers | ALLEXCEL INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20120100103-A1 | IN SITU FORMING HYDROGEL AND BIOMEDICAL USE THEREOF | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2012-04-26 | — | — | US | disclosed |
| US-7960498-B2 | Tissue adhesives with modified elasticity | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2011-06-14 | — | — | US | disclosed |
| US-20100260743-A1 | Solubilization and Targeted Delivery of Drugs With Self-Assembling Amphiphilic Polymers | ALLEXCEL, INC. (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100239659-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTI-CANCER AGENTS | ALLEXCEL., INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100008938-A1 | SELF ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS | ALLEXCEL, INC. | 2010-01-14 | — | — | US | disclosed |
| US-20080004421-A1 | Tissue adhesives with modified elasticity | ACTAMAX SURGICAL MATERIALS, LLC | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100103-A1 | IN SITU FORMING HYDROGEL AND BIOMEDICAL USE THEREOF | CD44, MYB, PLOD3 | PHF8 802/4885KDM2A 2354/4885EGLN1 247/4885 |
| US-20100008938-A1 | SELF ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS | PICALM, CLTA, HAVCR2 | PHF8 2495/4885KDM2A 4084/4885EGLN1 4108/4885 |
| US-20100239659-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTI-CANCER AGENTS | CD44, EPCAM, EGFR | PHF8 2908/4885KDM2A 4561/4885EGLN1 4706/4885 |
| US-20120156164-A1 | IN SITU-FORMING HYDROGEL FOR TISSUE ADHESIVES AND BIOMEDICAL USE THEREOF | CD44, DBH, TYR | PHF8 1273/4885KDM2A 1034/4885EGLN1 1630/4885 |
| US-20100260743-A1 | Solubilization and Targeted Delivery of Drugs With Self-Assembling Amphiphilic Polymers | CD44, ABCG2, ABCC1 | PHF8 3304/4885KDM2A 4796/4885EGLN1 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.