Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221665 | 0.81 | CASP1 (0.34) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL29499603 | 0.81 | CASP1 (0.34) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL5991120 | 0.80 | CASP1 (0.33) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2786924 | 0.78 | PRKCI (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL5992940 | 0.76 | PRKCI (0.30) | — | |
| SCHEMBL9984014 | 0.76 | CYP3A4 (0.47) | ADRA2BALDH1A1MAPTMAPK1 | |
| SCHEMBL22474145 | 0.75 | MAPT (0.46) | ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL9492082 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPT | |
| SCHEMBL9386593 | 0.73 | ADRA2B (0.32) | ADRA2B | |
| SCHEMBL7768063 | 0.72 | CYP19A1 (0.44) | ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917037-A | Process for the preparation of n-carboxyalkyl-3-fluoro-4-dialkylaminoanilines | CLARIANT GMBH (DE) | 1999-06-29 | — | — | US | disclosed |