Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524088 | 0.83 | HCRTR2 (0.41) | ALDH1A1HCRTR2 | |
| SCHEMBL8311002 | 0.81 | HTT (0.34) | KMT2ATP53MEN1TSHRHSD17B10 | |
| SCHEMBL8524690 | 0.80 | CA1 (0.40) | KMT2ATP53MEN1ALOX12GAA | |
| SCHEMBL8307229 | 0.79 | TSHR (0.32) | KMT2AMEN1TSHRHSD17B10KDM4E | |
| SCHEMBL8307727 | 0.79 | ALDH1A1 (0.32) | KMT2AMEN1TSHRHSD17B10KDM4E | |
| SCHEMBL8524686 | 0.77 | TP53 (0.38) | KMT2ATP53MEN1ALOX12TSHR | |
| SCHEMBL8747816 | 0.70 | ELANE (0.42) | KMT2ATP53MEN1ALOX12GAA | |
| SCHEMBL6292090 | 0.69 | HTT (0.39) | KMT2AMEN1TSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL8490050 | 0.68 | CNR2 (0.43) | KDM4EALDH1A1POLBELANE | |
| SCHEMBL8890586 | 0.68 | ALDH1A1 (0.37) | TP53ALOX12TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |